There are some 1h blunt (Allin's Mace) and swords (Iris Blade) that have the Rune Effect that require bloodstones and jaspers, to name a few.
Thristram: The necro spell
Summon Corpse needs tiny coffins and jade coffins to summon a corpse depending on the summoned corpse level. The epic effects are all passive and clicky DoTs.