I've had this problem recently on two installs on two different machines, and on both it seemed to have been caused by widescreen monitor resolutions. if you're using a widescreen, or a funky resolution, maybe try dropping it down to 1024x768, starting the game, setting the windowed and full screen resolutions to the widescreen resolution in-game, and then changing the windows resolution back.
*shrug* might have nothing to do with your problem, but it's worth a shot.
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